Senior Principal Scientist/Principal Scientist I/II

Job ID REQ-10079216 Jul 02, 2026 Switzerland Available in: English Summary ### Job Title: Senior Principal Scientist/Principal Scientist I/II, Oncology (RLT) \#LI-Onsite Location: Basel, Switzerland Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible. Shape the future of cancer treatment by driving innovative radioligand therapies from discovery to clinic. As a scientific leader within our Oncology Drug Discovery team in Basel, you will lead cutting-edge preclinical research, designing impactful in vivo studies and collaborating across global, multidisciplinary teams to unlock the potential of next-generation cancer treatments. This role offers a unique opportunity to combine scientific excellence with leadership-mentoring talent, influencing strategy, and translating complex data into meaningful insights that accelerate life-changing therapies for patients worldwide. About the Role ### Key Responsibilities • Design and lead in vivo studies supporting preclinical evaluation of radioligand therapies • Drive efficacy, biodistribution, imaging, and mechanism of action studies across oncology programs • Collaborate with cross-functional teams to advance drug candidates toward clinical development • Manage external partnerships with contract research organizations and academic collaborators • Mentor, guide, and develop scientists to strengthen scientific and professional capabilities • Present data and insights clearly to influence decisions across global research and development teams Essential Requirements • Doctor of Philosophy in Pharmacology, Cell Biology, or a related biomedical discipline • Minimum three years of additional experience in biomedical research within academia or industry • Strong background in cancer biology with a proven track record of scientific achievement • Extensive experience designing and managing in vivo oncology studies, including efficacy and pharmacokinetic assessment • Expertise in ex vivo analysis methods such as flow cytometry, immunofluorescence, immunohistochemistry, or RNA sequencing • Demonstrated ability to collaborate effectively within multidisciplinary and global research teams • Excellent communication and presentation skills in English, both written and verbal • Self-motivated, proactive, and able to independently drive scientific projects forward Desirable Requirements • Experience in radioligand therapy development or radiobiology • Strong understanding of drug development within oncology or related therapeutic areas This is a dual level posting. The final level and title for this position will be determined following the completion of the candidate evaluation process, based on skills, experience, and organizational needs The salary for this position is expected to range between: Principal Scientist: 93,800 to 174,200 CHF per year. Senior Principal Scientist: 122,500 to 227,500 CHF per year Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion\_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.  Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Learn about all the ways we-ll help you thrive personally and professionally. Read our handbook (PDF 30 MB) Primary location salary range CHF122,500.00 - CHF227,500.00 Division Biomedical Research Business Unit Research Location Switzerland Site Basel (City) Company / Legal Entity C028 (FCRS = CH028) Novartis Pharma AG Functional Area Research & Development Job Type Full time Employment Type Regular Shift Work No Research & Development Biomedical Research Switzerland Job ID REQ-10079216 Senior Principal Scientist/Principal Scientist I/II ### Apply to Job (link is external)